Evaluation of 2,6-diacetylpyridinebis-4-phenyl-3-thiosemicarbazone as complexing reagent for zinc in food and environmental samples

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Studies of Zinc(II) in Pharmaceutical and Biological Samples by Extractive Spectrophotometry: Using Pyridoxal-4-phenyl-3-thiosemicarbazone as Chelating Reagent

Piridoxal-4-fenil-3-tiossemicarbazona (PPT) é proposto como um novo reagente sensível para a determinação espectrofotométrica de zinco(II). PPT reage com zinco(II) no intervalo de pH entre 5,0 e 6,0, para formar um complexo colorido amarelo, o qual foi adequadamente extraído em n-butanol. A absorbância do complexo Zn(II)-PPT foi medida em diferentes intervalos de tempo, a 430 nm, para averiguar...

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Synthesis and Anticonvulsant Activity Evaluation of 3-alkoxy-4-(4- (hexyloxy/heptyloxy)phenyl)-4H-1,2,4 -triazole

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Synthesis and Anticonvulsant Activity Evaluation of 3-alkoxy-4-(4- (hexyloxy/heptyloxy)phenyl)-4H-1,2,4 -triazole

A series of 3-alkoxy-4-(4-(hexyloxy/heptyloxy) phenyl)-4H-1,2,4-triazole was synthesized. The anticonvulsant effect and neurotoxicity of the compounds were calculated with maximal electroshock (MES) test and rotarod tests with intraperitoneally injected mice. Among the synthesized compounds, compound 3-heptyloxy-4-(4-(hexyloxy) phenyl)-4H-1,2,4-triazole (5f) was the most active one and also had...

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ژورنال

عنوان ژورنال: Journal of Saudi Chemical Society

سال: 2016

ISSN: 1319-6103

DOI: 10.1016/j.jscs.2012.11.004